Everything you need to know about DMT ( Hallucinogenic Tryptamine Drugs)
DMT. What is DMT, and how does it affect individuals who abuse it? N, N-dimethyltryptamine or DMT is a popular and powerful psychedelic substance with a Schedule III classification under Canada’s Controlled Drugs and Substances Act. Dealers also call DMT drugs “the spirit molecule” or “the businessman’s trip.”
Here’s a complete guide to DMT (Dimethyltryptamine) — one of the most powerful and intriguing psychedelic substances known.
What is N, N-dimethyltryptamine?
DMT, or N, N-Dimethyltryptamine, is a potent hallucinogen that is both synthesized in labs and found naturally in various plants and animals. DMT is renowned for its intense psychoactive properties. It is the primary psychedelic compound in the South American plant brew known as ayahuasca, which has been used for centuries in religious and spiritual practices. DMT is classified as a Schedule I substance in the United States. However, certain protections exist for its use in religious ceremonies and research.
Effects of N, N-dimethyltryptamine – DMT
When consumed, DMT induces a range of desired and undesired effects. Among the most common desired effects are vivid hallucinations, dissociation from the body, alterations in mood, and significant changes in perception. Users often report experiencing a profound shift in consciousness, a sense of connection to the universe, altered visual and auditory experiences, and intense emotional states. However, there are also unwanted effects, such as nausea, vomiting, elevated blood pressure, and increased heart rate.
In extreme cases, DMT use has been linked to severe reactions, including seizures, respiratory arrest, and even cardiac arrest. These more dangerous outcomes are rare but have been reported to poison control centers, highlighting the risks associated with the substance.

History of N, N-dimethyltryptamine
The use of DMT dates back centuries, with indigenous South American tribes using brews like ayahuasca in religious ceremonies. The brew contains two primary ingredients: Psychotria viridis, a shrub rich in DMT, and Banisteriopsis caapi, a vine that contains monoamine oxidase inhibitors (MAOIs). These MAOIs prevent the rapid breakdown of DMT in the body, allowing for the prolonged and intense effects of the brew.
In the 1930s, ayahuasca began to make its way into urban Brazil, where it was used in religious environments. The first synthesis of DMT occurred in the 1950s, and by the 1960s, its hallucinogenic properties were widely recognized. DMT’s popularity increased in the United States in the 1960s as a recreational drug. However, in 1971, the passage of the Controlled Substances Act led to DMT being classified as a Schedule I substance, making it illegal for most uses.
The Resurgence of Psychedelics – DMT
In recent years, there has been a resurgence of interest in psychedelics, including N, N-dimethyltryptamine
. This revival includes both recreational use and the exploration of DMT’s therapeutic potential. With a relatively short duration of action, DMT is considered a more appealing alternative to other psychedelics that have longer-lasting effects. It is also becoming increasingly available, both for recreational use and through religious practices, such as ayahuasca ceremonies.
Despite its rise in interest, the use of DMT remains relatively low compared to other substances. However, recent statistics show a gradual increase in its use, especially among individuals who use other substances. From 2007-2014, tryptamine use (which includes DMT) increased from 0.2% to 0.7%, according to the National Survey on Drug Use and Health. Furthermore, there has been a notable increase in ayahuasca-related calls to poison control centers, particularly between 2005 and 2015, further demonstrating the growing prevalence of N, N-dimethyltryptamine-related incidents.
What does it look like?
DMT is found in a variety of plants and animals, and is the psychoactive ingredient in the drug ayahuasca. In ayahuasca, a plant containing DMT is boiled together with a plant containing a monoamine oxidase inhibitor (MAOI) such as harmaline, and the mixture is drunk.
When produced synthetically DMT is a white crystalline powder.
Other names
Dimitri, Deems The spirit molecule, Changa, Fantasia, the glory, the sacrament
Other types of psychedelics – Tryptamine For Sale
- 2C-B
- Ayahuasca
- LSD
- Mescaline
- NBOMes
- Psilocybin (magic mushrooms)
- Salvia
How is used?
DMT can be:
- vaporised or smoked in a pipe
- drunk as part of an ayahuasca brew
- snorted
- injected.
Effects
Use of any drug can have risks. It’s important to be careful when taking any type of drug.
Psychedelics affect everyone differently, based on:
- size, weight and health
- whether the person is used to taking it
- whether other drugs are taken around the same time
- the amount taken
- the strength of the drug (varies from batch to batch)
- environment (where the drug is taken).
DMT is most commonly smoked in Australia, with effects commencing almost straight away and finishing after around 30 minutes. Effects may include:
- a ‘rush’
- feeling happy and excited
- changes in mood
- increased sensitivity to bodily sensations (body aches, tingles, feelings of pain and pleasure, warmth and fatigue)
- increased heart rate and blood pressure
- small pupils
- anxiety and confusion
- intense visual hallucinations
- dissociation.
Impact of mood and environment – DMT
Drugs that affect a person’s mental state (psychoactive drugs) can also have varied effects depending on a person’s mood (often called the ‘set’) or the environment they are in (the ‘setting’):
- Set: a person’s state of mind, previous encounters with psychedelic drugs, and expectations of what’s going to happen. For example, feelings of stress or anxiety before using DMT may result in an unpleasant experience (bad trip).7
- Setting: the environment in which someone consumes a psychedelic drug – whether it’s known and familiar, who they’re with, if they’re indoors or outdoors, the type of music and light. For example, using DMT in a calm, quiet and relaxed environment can lead to, or contribute to, a pleasant experience but being in a noisy, crowded place may result in a negative experience.
- Being in a good state of mind, with trusted friends and a safe environment before taking DMT reduces the risk of having a ‘bad’ trip.
Overdose
If someone takes a large amount, the negative effects of DMT are more likely. Call an ambulance straight away by dialling triple zero (000) if you or someone else has any of these symptoms (Emergency services are there to help and can provide instructions over the phone):
- vomiting
- inability to move
- intense anxiety and confusion
- overwhelming fear and paranoia
- psychosis
- increased risk-taking
Bad trips
Some people may have negative experiences taking any psychedelics, or experiences they find challenging. This can happen even if a person takes a moderate dose. During a bad trip, you may experience frightening or confronting hallucinations, and feelings of anxiety, confusion, fear and paranoia.
Coming down – DMT
There is little data on the comedown effects of N, N-dimethyltryptamine, but anecdotal user reports suggest that you may experience:
- feeling a bit confused and unable to think clearly
- trouble concentrating
- feeling anxious or panicked
- feeling disconnected with your body
- racing thoughts or realisations
- trouble sleeping.
Long-term effects
The most common long-term effect of psychedelic use is ‘flashbacks’. Flashbacks are a re-experience of the drug and can occur days, weeks, months and even years later after using.
Flashbacks can be triggered by the use of other drugs or by stress, fatigue or physical exercise. The flashback experience can range from being pleasant to causing severe feelings of anxiety. They are usually visual and last for a minute or two.6,8
There have been no reports of toxic effects from the long-term use of DMT, aside from concerns regarding the cardiovascular impact of increased heart rate and blood pressure. Buying dmt
N, N-dimethyltryptamine and mental health
For people with a history of mental health concerns, or a current condition, DMT can worsen symptoms in some cases.
Tolerance and dependence
Reports suggest that DMT does not produce any tolerance, and there is low potential for dependence to occur.13
Mixing N, N-dimethyltryptamine with other drugs – DMT
Mixing DMT with other drugs can have unpredictable effects and increase the risk of harm.
- DMT and Tramadol: may cause seizures.
- DMT and Cannabis: risk of anxiety, paranoia, panic, psychosis.
- DMT and ice/speed/cocaine: can increase risk of anxiety & negative thought loops, leading to a negative experience.
Reducing Harm
There are ways you can reduce the risk of harm when taking N, N-dimethyltryptamine:
- Do your research first around the correct form of DMT to use, as well as what is a suitable dose and the safest method of use.
- Start with a lower dose until you know how the drug affects you personally. It will be different for everyone.
- Use around people you trust in a comfortable and safe environment
- Find a quiet relaxing place where you can sit or lie down if needed as the experience can be overwhelming and disorientating.
- Consider having a person to ‘trip sit’. A person who remains sober and that can help out if needed.
- If you’re not in a good frame of mind, consider whether it is the right time to take N, N-dimethyltryptamine.
Withdrawal
According to user reports, DMT does not cause any physical withdrawal symptoms. However, some people who use DMT may feel like they need it again for ‘insight’ or to have another meaningful experience.
Getting Help – DMT
If your use of DMT is affecting your health, family, relationships, work, school, financial or other life situations, or you’re concerned about someone else, you can find help and support.
- Call the National Alcohol and Other Drug Hotline on 1800 250 015 for free and confidential advice, information and counselling about alcohol and other drugs
- Help and Support Services search. Find a service in your local area from our list. Simply add your location or postcode and filter by service type to quickly discover help near you.


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